Here’s the first look at the trailer for The Rum Diary, starring Johnny Depp. Based on Hunter S. Thompson’s novel, the story centers on a journalist who escapes the noise of New York City and conventional America in the late 1950s to explore Puerto Rico and write for a local newspaper.

The romp costars Amber Heard (Pineapple Express), Aaron Eckhart (The Dark Knight), Richard Jenkins (Eat Pray Love), Michael Rispoli (Kick-Ass) and Giovanni Ribisi (Avatar). It was written and directed by Bruce Robinson (Withnail & I, Jennifer 8).

Narrated by Depp, the footage shows the writer at a turning point, succumbing to the debauched lifestyle of the questionable characters, getting involved with a woman engaged to a shady businessman, and finding his mission amidst the madness.

The book was published in 1998, after Depp discovered Thompson’s manuscript when preparing for his role in the film version of the author’s Fear and Loathing in Las Vegas.

The Rum Diary opens in North America on October 28, the UK on November 4, France on November 30, and other markets through December and into 2012.